The AI-fication of Cyberthreats: Trend Micro Security Predictions for 2026

For 2026, we’ve chosen to spotlight advanced persistent threats (APTs) because they remain the most persistent and politically charged form of cyber conflict, where innovation, espionage, and global power dynamics collide. These campaigns no longer unfold quietly in the shadows; they are becoming faster, smarter, and more interconnected than ever before.

We foresee threat actors using large language models (LLMs) to analyze stolen data to identify valuable intelligence and even use them to learn from authentic communication content to craft more convincing phishing content that victims are more likely to believe.

Generative models will be able to craft nearly flawless phishing lures, while AI-driven reconnaissance will map entire networks with great accuracy. Attackers will adopt AI-powered living-off-the-land techniques, using LLMs to generate commands that mimic legitimate activity and evade detection. Compromised enterprise AI models and poisoned supply chains will further become powerful enablers, allowing attackers to weaponize trust itself and spread compromise across industries.

Even the human factor is being reimagined. Nation-state actors now use AI to forge synthetic identities and deepfake-assisted personas capable of infiltrating organizations from within. Once inside, they can quietly alter code, steal data, or sabotage systems under the guise of legitimate work. In 2026, APTs will not only evolve, but also adapt.

In the race toward digital transformation, enterprises are pushing boundaries faster than ever before. But every leap in innovation comes with an equal measure of risk, as the same technologies driving efficiency also open new pathways for exploitation.

Many organizations still rely on unpatched servers, deprecated software, and hardware that weren’t designed for today’s hyperconnected environments. What once appeared to be manageable IT debt has evolved into a growing liability, with attackers increasingly targeting forgotten APIs, misconfigured cloud services, and neglected edge devices. At the same time, identity has become a central pressure point in enterprise security. AI-driven social engineering now enables attackers to convincingly imitate trusted users, making it harder to detect. Meanwhile, identity systems originally designed for human users are now being extended to manage autonomous agents that hold significant access rights, creating new challenges for controlling privileges and preventing lateral movement.

This is why we’ve turned our attention to enterprise threats: In 2026, a large portion of the threats to enterprises will come from within, such as the silent misuse of trusted systems, compromised automation pipelines, and insiders (human or AI) operating under legitimate credentials. The line between business process and attack vector is blurring.

As organizations pour their most critical operations into cloud platforms, threat actors are following close behind by probing, exploiting, and adapting more and more quickly. Despite widespread multi-cloud adoption, nearly half of organizations still lack full visibility into their cloud assets, leaving blind spots that enable cross-platform attacks. What began as a story of transformation has become a story of exposure. For our 2026 predictions, we’ve chosen to focus on cloud threats because they now sit at the core of digital transformation, where a single misstep in configuration or identity management can cascade into massive disruption across industries.

In the year ahead, attackers will weaponize everything from advanced phishing kits and poisoned container images to multi-cloud misconfigurations and exposed credentials. Hybrid environments will grow so complex that even seasoned defenders might struggle to maintain full visibility of what’s running, and where. Meanwhile, cloud-based GPU systems will emerge as prime targets, coveted for both their compute power and the sensitive data that might linger in shared memory. Each new service, API, and integration point will expand the cloud’s connectivity and, with it, its vulnerabilities.

This rising complexity is what will make the cloud threat landscape impossible to ignore in 2026. Misconfigurations, overprivileged accounts, and hybrid blind spots will continue to act as the enablers of major breaches. As attackers exploit trust relationships and automation pipelines, defenders will race to keep pace in an ecosystem that never stops changing.

In addition to being one of the most prevalent modern threats, ransomware represents a perfect storm of automation, AI, and exploitation, where the traditional cybercrime model is combined with autonomous systems capable of running attacks end to end. As payment rates fall and defenders improve, threat actors will look for new avenues of monetization: exposing stolen data, manipulating media, and using AI to personalize coercion in real time.

We foresee ransomware operations exploiting supply chains, poisoned software updates, and cloud services to silently infiltrate trusted ecosystems. Attackers will rent cloud GPUs, automate data mining, and hijack legitimate infrastructure to maximize impact. Meanwhile, the rise of AI-powered ransomware-as-a-service (RaaS) will lower the barrier to entry for ransomware operations, allowing anyone with access to automated tools to launch sophisticated campaigns, fueling a surge in smaller, faster, and more unpredictable attacks.

This is why ransomware will remain a defining threat of the cybersecurity landscape even in the coming year. It’s evolving from a disruptive event into a systemic issue. Every enterprise dependency, from AI models and supply chains to APIs and even business relationships, will double as an attack surface. The future of ransomware isn’t about just encryption, but also the exploitation of trust itself. For enterprises, the real danger lies in the aftermath: the prolonged operational paralysis, data exposure, and erosion of stakeholder trust that follow each attack.

Vulnerabilities figure in our 2026 security predictions because they represent the foundation of every major breach, the often unseen weaknesses that automation and AI now exploit at unprecedented speed. Vulnerabilities are no longer limited to traditional software; they now extend to the logic, data, and code that drive AI itself.

In 2026, attackers will use AI to discover and weaponize vulnerabilities faster than defenders can respond to them. The same automation that powers innovation will amplify exploitation, allowing threat actors to instantly scan, test, and adapt exploits at scale. Even familiar issues, such as SQL injection or misconfigured APIs, will resurface in new, AI-enabled forms. Meanwhile, unsecure AI-generated code created through vibe coding will silently introduce bugs and backdoors into production environments, compounding systemic risk across the supply chain.

The impact will be felt far beyond the IT stack. A single flaw in an open-source package, inference engine, or third-party library can cascade across industries, disrupting services and eroding trust. As patching windows shrink and exposure grows, enterprises will struggle to balance innovation with security. In 2026, managing vulnerabilities will mean keeping pace with an attack surface where a single oversight in code, model, or configuration can trigger disruption across organizations.